Education:
• Postdoctoral scholar (2005-2009), McKerrow laboratory, Sandler Center for Drug Discovery at the University of California San Francisco, USA (now The Center for Discovery and Innovation in Parasite Diseases. UC San Diego) www.cdipd.org
• Ph.D. (2005) in parasitology, Charles University, Faculty of Science, Department of Parasitology, Prague (Thesis: Characterization of Schistosomal Peptidases and Their Role in Host - Parasite interactions).
• M.Sc. (2000) in biology – parasitology, Charles University, Faculty of Science, Department of Parasitology, Prague
• B.Sc. (1997) in biology Charles University, Faculty of Science, Prague
WORK EXPERIENCE:
2017 - present
Head of Laboratory of Molecular Helminthology, Czech University of Life Sciences Prague, Czech Republic.
2018-2019
part time, Institute of Specific Prophylaxis and Tropical Medicine, Medical University Vienna, Austria.
2013-present
part time, Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences
2016-2017
Researcher, Institute of Molecular Genetics, Czech Academy of Sciences, Prague, Czech Republic.
2014 - 2016
Visiting researcher, Dalton laboratory, Medical Biology Centre
School of Biological Sciences, Queen's University Belfast, Northern Ireland
2011 - 2014
Researcher, Institute of Molecular Genetics, Czech Academy of Sciences, Prague, Czech Republic.
2009 - 2012 Head of Laboratory of Molecular Helminthology, Institute of Parasitology, Biology Centre, Czech Academy of Sciences, České Budějovice, Czech Republic. (until the end of 2012).
S. mansoni bioactive molecules in proteolysis involved in host/parasite interactions.
2005-2009 Postdoctoral Scholar, McKerrow laboratory, University of California, San Francisco, USA. http://www.cdipd.org/
Tool development for transgenesis in human schistosomes using biolistic and lentivirus.
Characterization of schistosome proteolytic enzymes involved in pathogenesis.
Optimization of RNAi knockdown in schistosomes.
Characterization of digestive proteolytic enzymes from hard tick Ixodes ricinus.
2003-2005 Research assistant, Department of Parasitology, Faculty of Science, Charles University Prague, Czech Republic. http://www.helminthology.cz/
Proteolytic enzymes of neuropathogenic schistosome Trichobilharzia regenti.
