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doc. Ing. Jaroslav Havlik, Ph.D.
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Publikace

Seznam publikací (2020–2026)

Aktualizováno v srpnu 2026.

2026

  1. Chowdhury, C.R., Havlik, J. Beyond sweetness: a review of the health and safety of acesulfame-K. Food Chemistry, 147290.

  2. Tomisová, K., Mascellani Bergo, A., Jarošová, V., Cinek, O., Hlináková, L., …, Havlik, J. In vitro gut microbial catabolism of ferulic acid is characterized by interindividual variability. npj Science of Food, 10(1), 71.

  3. Hernandez Olesinski, E.J., Mascellani Bergo, A., Barbagli, T., Havlik, J., et al. Nitrate availability influences powdery mildew resistance and secondary metabolism in Gerbera hybridaFrontiers in Plant Science, 17, 1879542.

  4. Rysová, L.K., Cejnar, P., Legarová, V., Hanuš, O., Mascellani Bergo, A., Havlik, J., et al. Centrifugation-induced somatic cell count reduction in milk as a form of adulteration detected by ¹H NMR spectroscopy and multivariate modeling. Journal of Dairy Science.

  5. Mattila, M., Tapia, G., Størdal, K., Brantsæter, A.L., Virtanen, S.M., Lund-Blix, N.A., et al. (incl. Havlik, J.). Maternal intake of vitamins A, C, D, and E during pregnancy and the risk of type 1 diabetes in the child: the Norwegian Mother, Father and Child Cohort Study. The American Journal of Clinical Nutrition, 101431.

  6. Brenner, D., Mascellani Bergo, A., Řehůřková, E., Havlik, J., Babica, P., Sovadinová, I. A robust dynamic 3D liver spheroid platform for (sub)chronic toxicity assessment: metabolic characterization of HepG2 spheroids as a case study. Toxicology, 154538.

  7. Jiménez-Viveros, Y., Mascellani Bergo, A., Havlik, J., Valiente-Banuet, J.I. Stage-specific metabolic responses of piquin peppers to colored shading nets across fruit maturation revealed by ¹H NMR metabolomics. Chemical and Biological Technologies in Agriculture.

  8. Lee, S., Dobeš, P., Mascellani Bergo, A., Killer, J., Marciniak, J., Hurychová, J., …, Havlik, J. Bacterial supplementation shapes honey bee gut microbiota and host metabolism under controlled and field conditions. mSystems, 11(6), e00283-26.

  9. Jeníčková, E., Mascellani Bergo, A., Chowdhury, C.R., Havlik, J. The faecal bulk heterogeneity: implications for homogenisation and spot-sampling strategies for metabolomic investigations. Metabolomics, 22(3), 84.

  10. Roy Chowdhury, C., Mascellani Bergo, A., Jeníčková, E., Knížková, Š., Havlik, J. Impact of short-term Gala apple intake on the human faecal metabolome assessed by ¹H NMR spectroscopy. Nutrients, 18(9), 1312.

  11. Werle, J., Mascellani Bergo, A., Houdková, M., Havlik, J., Kokoška, L. Relationship between chemical structure and growth-inhibitory activity of monoterpenoids against pneumonia-causing bacteria in vapor phase. Bioorganic & Medicinal Chemistry Letters, 130663.

  12. Hurychová, J., Marciniak, J., Ward, R., Lee, S., Šreibr, S., Moutelíková, R., Hyršl, P., …, Havlik, J. Seasonal trade-offs shape metabolomic and proteomic responses to Varroa destructor parasitisation in honey bees (Apis mellifera). Insect Biochemistry and Molecular Biology, 104535.

  13. Reinhardt Piskáčková, T., Mascellani Bergo, A., Jurkaninová, L., Havlik, J. Trade-offs in organic wheat: lower protein quality versus enhanced prebiotic oligosaccharides. Journal of Agricultural and Food Chemistry, 74(10), 8636–8646.

  14. Clerbaux, L.A., Nissen, L., Acedo, P., Hitch, T., Carillo, E., Ibrahimi, E., Ponsero, A., et al. (incl. Havlik, J.). INFOGUT — International networking on in vitro colon models simulating gut microbiota-mediated interactions — 1st Annual Meeting. ALTEX, 43(3), 519–522.

2025

  1. McKirdy, S., Koutsos, A., Nichols, B., Anderson, M., Dhami, S., Chowdhury, C.R., …, Havlik, J., Gerasimidis, K. Micronutrient supplementation influences the composition and diet-originating function of the gut microbiome in healthy adults. Clinical Nutrition, 51, 293–303.

  2. Dengiz, B., Killer, J., Havlik, J., Dobeš, P., Hyršl, P. Selection of probiotics for honey bees: the in vitro inhibition of Paenibacillus larvaeMelissococcus plutonius and Serratia marcescens strain Sicaria by host-associated lactic acid bacteria. Microorganisms, 13(5), 1159.

  3. Čmiková, N., Vukić, M.D., Vuković, N.L., Havlik, J., Noguera-Artiaga, L., et al. Biochemical profiling and bioactivity of five selected microalgae species as potential sources of bioactive compounds for nutritional and biotechnological applications. Journal of Food Biochemistry, 2025(1), 5171615.

  4. Marasco, P., Kozlu, A., Mascellani Bergo, A., Havlik, J., Klojdová, I., Baigts-Allende, D.K. Structural and functional qualities of gelatin derived from the skin of the common eland antelope (Taurotragus oryx). Food Hydrocolloids, 167, 111397.

  5. Neuman, V., Maratová, K., Plachý, L., Drnková, L., Průhová, Š., Koloušková, S., et al. (incl. Havlik, J.). Short-term low-carbohydrate diet decreases body weight and fat mass but not muscle strength in children and young people with type 1 diabetes. European Journal of Clinical Nutrition, 79(11), 1149–1153.

  6. Sozzi, M., Aru, V., Mascellani Bergo, A., Cavallini, N., Savorani, F., Havlik, J., et al. Using experimental design and ¹³C satellites to optimize the measurement of the absolute concentration of ethanol in wine by ¹H NMR spectroscopy. Food Research International, 214, 116598.

  7. Čmiková, N., Vukić, M.D., Vuković, N.L., Havlik, J., Issa-Issa, H., et al. Metabolomic approach to explore the chemical composition and health benefits of macroalgae: a comprehensive study of Palmaria palmataAscophyllum nodosum and Chondrus crispusFood Chemistry, 146436.

  8. Čmiková, N., Vukić, M.D., Vuković, N.L., Havlik, J., Noguera-Artiaga, L., et al. Comprehensive analysis of Chlorella vulgaris and Arthrospira platensis: algae for food well-being and sustainable agriculture. ACS Food Science & Technology, 5(8), 3000–3011.

  9. Kozlu, A., Ngasakul, N., Klojdová, I., Havlik, J., Mascellani Bergo, A., Berčíková, M., et al. Overall use of edible insects for producing food analogs and upcycling insect-derived ingredients from residues. Applied Food Research, 5(1), 100881.

  10. Davison, S., Mascellani Bergo, A., Ward, Z., Sackett, A., Stryková, A., Jaimes, J.D., et al. (incl. Havlik, J.). Cardiometabolic disease risk in gorillas is associated with altered gut microbial metabolism. npj Biofilms and Microbiomes, 11(1), 33.

  11. Kačániová, M., Škultétyová, M., Tvrdá, E., Benko, F., Ďuračka, M., Čmiková, N., et al. (incl. Havlik, J.). Nutritional value and chemical properties of drone milk as a source of probiotics and evaluation of antioxidant effects on reproductive structures by in vitro test. Process Biochemistry, 149, 144–157.

  12. Mascellani Bergo, A., Taglieri, I., Venturi, F., Matak, L., Gondáš, P., Klouček, P., Havlik, J. ¹H NMR spectrum carries signatures of white wine aroma. LWT, 223, 117786.

  13. Gupta, N., Bhattacharya, S., Žiarovská, J., Dutta, A., Fialková, V., Farkasová, S., et al. (incl. Havlik, J.). Oryzalin-induced polyploidy enhances natural metabolite accumulation and functional bioactivities in novel Callisia fragrans genotype. Scientific Reports, 15(1), 25652.

2024

  1. Nichols, B., Briola, A., Logan, M., Havlik, J., Mascellani, A., Gkikas, K., Milling, S., et al. Gut metabolome and microbiota signatures predict response to treatment with exclusive enteral nutrition in a prospective study in children with active Crohn's disease. The American Journal of Clinical Nutrition, 119(4), 885–895.

  2. Mascellani Bergo, A., Leiss, K., Havlik, J. Twenty years of ¹H NMR plant metabolomics: a way forward toward assessment of plant metabolites for constitutive and inducible defenses to biotic stress. Journal of Agricultural and Food Chemistry, 72(15), 8332–8346.

  3. Hurych, J., Mascellani Bergo, A., Lerchová, T., Hlináková, L., Kubát, M., et al. (incl. Havlik, J.). Faecal bacteriome and metabolome profiles associated with decreased mucosal inflammatory activity upon anti-TNF therapy in paediatric Crohn's disease. Journal of Crohn's and Colitis, 18(1), 106–120.

  4. Kerbiriou, C., Dickson, C., Nichols, B., Logan, M., Mascellani, A., Havlik, J., et al. Treatment of active Crohn's disease with exclusive enteral nutrition diminishes the immunostimulatory potential of fecal microbial products. Inflammatory Bowel Diseases, 30(12), 2457–2466.

  5. Neuman, V., Plachý, L., Drnková, L., Průhová, Š., Koloušková, S., et al. (incl. Havlik, J.). Low-carbohydrate diet in children and young people with type 1 diabetes: a randomized controlled trial with cross-over design. Diabetes Research and Clinical Practice, 217, 111844.

  6. Lee, S., Dobeš, P., Marciniak, J., Mascellani Bergo, A., Kamler, M., Maršík, P., Pohl, R., et al. (incl. Havlik, J.). Phytochemical S-methyl-L-cysteine sulfoxide from Brassicaceae: a key to health or a poison for bees? Open Biology, 14(12), 240219.

  7. Tomisová, K., Jarošová, V., Maršík, P., Mascellani Bergo, A., Cinek, O., Hlináková, L., et al. (incl. Havlik, J.). Mutual interactions of silymarin and colon microbiota in healthy young and healthy elder subjects. Molecular Nutrition & Food Research, 68(22), 2400500.

  8. Hakola, L., Lund-Blix, N.A., Takkinen, H.M., Tapanainen, H., Niinistö, S., et al. (incl. Havlik, J.). Maternal gluten, cereal, and dietary fiber intake during pregnancy and lactation and the risk of islet autoimmunity and type 1 diabetes in the child. Clinical Nutrition ESPEN, 62, 22–27.

2023

  1. Kunc, M., Dobeš, P., Ward, R., Lee, S., Čegan, R., Dostálková, S., Holušová, K., et al. (incl. Havlik, J.). Omics-based analysis of honey bee (Apis mellifera) response to Varroa sp. parasitisation and associated factors reveals changes impairing winter bee generation. Insect Biochemistry and Molecular Biology, 152, 103877.

  2. Jeníčková, E., Andrén Aronsson, C., Mascellani Bergo, A., Cinek, O., Havlik, J., et al. Effects of Lactiplantibacillus plantarum and Lacticaseibacillus paracasei supplementation on the faecal metabolome in children with coeliac disease autoimmunity. Frontiers in Nutrition, 10, 1183963.

  3. Mascellani, A., Mercl, F., Kurhan, S., Pierdonà, L., Kudrna, J., Zemanová, V., et al. (incl. Havlik, J.). Biochemical and physiological changes in Zea mays L. after exposure to the environmental pharmaceutical pollutant carbamazepine. Chemosphere, 329, 138689.

  4. Neuman, V., Průhová, Š., Kulich, M., Koloušková, S., Vosáhlo, J., Romanová, M., et al. (incl. Havlik, J.). Changes in the gut bacteriome upon gluten-free diet intervention do not mediate beta cell preservation. Diabetologia, 66(1), 241–246.

  5. Narra, F., Castagna, A., Palai, G., Havlik, J., Mascellani Bergo, A., D'Onofrio, C., Ranieri, A., et al. Postharvest UV-B exposure drives changes in primary metabolism, phenolic concentration and volatilome profile in berries of different grape (Vitis vinifera L.) cultivars. Journal of the Science of Food and Agriculture, 103(13), 6340–6351.

2022

  1. Šťastný, J., Maršík, P., Tauchen, J., Božik, M., Mascellani, A., Havlik, J., Landa, P., et al. Antioxidant and anti-inflammatory activity of five medicinal mushrooms of the genus PleurotusAntioxidants, 11(8), 1569.

  2. Rysová, L., Cejnar, P., Hanuš, O., Legarová, V., Havlik, J., Nejeschlebová, H., et al. Use of MALDI-TOF MS technology to evaluate adulteration of small ruminant milk with raw bovine milk. Journal of Dairy Science, 105(6), 4882–4894.

  3. Ruskovska, T., Budić-Leto, I., Corral-Jara, K.F., Ajdžanović, V., Arola-Arnal, A., et al. (incl. Havlik, J.). Systematic analysis of nutrigenomic effects of polyphenols related to cardiometabolic health in humans — evidence from untargeted mRNA and miRNA studies. Ageing Research Reviews, 79, 101649.

  4. Lee, S., Kalčic, F., Duarte, I.F., Titěra, D., Kamler, M., Mrna, P., Hyršl, P., Danihlík, J., et al. (incl. Havlik, J.). ¹H NMR profiling of honey bee bodies revealed metabolic differences between summer and winter bees. Insects, 13(2), 193.

  5. Mascellani, A., Leiss, K., Bac-Molenaar, J., Malaník, M., Maršík, P., et al. (incl. Havlik, J.). Polyketide derivatives in the resistance of Gerbera hybrida to powdery mildew. Frontiers in Plant Science, 12, 790907.

2021

  1. Mascellani, A., Hoca, G., Babisz, M., Krška, P., Klouček, P., Havlik, J. ¹H NMR chemometric models for classification of Czech wine type and variety. Food Chemistry, 339, 127852.

  2. Dostálková, S., Dobeš, P., Kunc, M., Hurychová, J., Škrabišová, M., et al. (incl. Havlik, J.). Winter honeybee (Apis mellifera) populations show greater potential to induce immune responses than summer populations after immune stimuli. Journal of Experimental Biology, 224(3), jeb232595.

  3. Jaimes, J.D., Slavíčková, A., Hurych, J., Cinek, O., Nichols, B., Vodolánová, L., et al. (incl. Havlik, J.). Stool metabolome-microbiota evaluation among children and adolescents with obesity, overweight and normal weight using ¹H NMR and 16S rRNA gene profiling. PLoS ONE, 16(3), e0247378.

  4. Rysová, L., Legarová, V., Pacáková, Z., Hanuš, O., Němečková, I., Klimešová, M., et al. (incl. Havlik, J.). Detection of bovine milk adulteration in caprine milk with N-acetyl carbohydrate biomarkers by using ¹H nuclear magnetic resonance spectroscopy. Journal of Dairy Science, 104(9), 9583–9595.

  5. Mascellani, A., Natali, L., Cavallini, A., Mascagni, F., Caruso, G., Gucci, R., et al. (incl. Havlik, J.). Moderate salinity stress affects expression of main sugar metabolism and transport genes and soluble carbohydrate content in ripe fig fruits (Ficus carica L.). Plants, 10(9), 1861.

  6. Houdková, M., Chaure, A., Doskočil, I., Havlik, J., Kokoška, L. New broth macrodilution volatilization method for antibacterial susceptibility testing of volatile agents and evaluation of their toxicity using modified MTT assay in vitro. Molecules, 26(14), 4179.

  7. Ruskovska, T., Budić-Leto, I., Corral-Jara, K.F., Ajdžanović, V., Arola-Arnal, A., et al. (incl. Havlik, J.). Systematic bioinformatic analyses of nutrigenomic modifications by polyphenols associated with cardiometabolic health in humans — evidence from targeted nutrigenomic studies. Nutrients, 13(7), 2326.

  8. Monfoulet, L.E., Ruskovska, T., Ajdžanović, V., Havlik, J., Vauzour, D., Bayram, B., et al. Molecular determinants of the cardiometabolic improvements of dietary flavanols identified by an integrative analysis of nutrigenomic data from a systematic review of animal studies. Molecular Nutrition & Food Research, 65(16), 2100227.

  9. Veselý, O., Maršík, P., Jarošová, V., Doskočil, I., Šmejkal, K., Klouček, P., Havlik, J. Metabolism of selected 2-arylbenzofurans in a colon in vitro model system. Foods, 10(11), 2754.

2020

  1. Havlik, J., Marinello, V., Gardyne, A., Hou, M., Mullen, W., Morrison, D.J., et al. Dietary fibres differentially impact on the production of phenolic acids from rutin in an in vitro fermentation model of the human gut microbiota. Nutrients, 12(6), 1577.

  2. Jarošová, V., Veselý, O., Doskočil, I., Tomisová, K., Maršík, P., Jaimes, J.D., et al. (incl. Havlik, J.). Metabolism of cis- and trans-resveratrol and dihydroresveratrol in an intestinal epithelial model. Nutrients, 12(3), 595.

  3. Valentová, K., Havlik, J., Kosina, P., Papoušková, B., Jaimes, J.D., Káňová, K., et al. Biotransformation of silymarin flavonolignans by human fecal microbiota. Metabolites, 10(1), 29.

  4. Urbanová, K., Klouček, P., Havlik, J., Valterová, I., Kokoška, L. Fast and ecological liquid-liquid separation method for preparing quinone-enriched extract from Nigella sativa oil. Journal of the Brazilian Chemical Society, 31(4), 739–745.